Причины появления, механизмы, скорость развития, пути распространения и последствия устойчивости к антибиотикам
Аннотация
Проблема антибиотикорезистентности сейчас как никогда актуальна. Кризис, связанный с распространением устойчивости к антибиотикам, приближается с каждым днем. Новых антибактериальных препаратов и методов, позволяющих эффективно бороться с устойчивыми микроорганизмами, не появляется, следовательно, появляется серьёзнейший вызов для всего человечества, так как от эффективности антибиотиков напрямую зависят такие важные для жизни человека сферы как медицина и сельское хозяйство.
Цель исследования. Данная статья позволяет сформировать системный взгляд на явление антибиотикорезистентности.
Материал и методы. Для анализа литературы были использованы материалы из ресурсов PubMed и PubMed Central Национальной медицинской библиотеки США, Google Scholar, Elsevier Clinical Key и Elsevier Science Direct. Выборку составили научные статьи, посвященные антибиотикорезистентности.
Результат. В статье раскрываются причины появления, механизмы, скорость развития, способы и пути распространения антибиотикорезистентности, а также последствия приобретения устойчивости для микроорганизмов и способы сдерживания антибиотикорезистентности.
Благодарности. Работа выполнена при поддержке Министерства науки и высшего образования Российской Федерации в рамках Программы развития Уральского федерального университета имени первого Президента России Б. Н. Ельцина в соответствии с программой стратегического академического лидерства "Приоритет-2030".
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Литература
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