AFFECTIVE DISORDERS IN MEN WITH ARTERIAL HYPERTENSION IN COMBINATION WITH METABOLIC SYNDROME

Keywords: metabolic syndrome, chronic ischemic heart disease, anxiety, depression

Abstract

Purpose. To study the features of affective disorders in men with comorbid chronic coronary heart disease with metabolic syndrome.

Materials and methods. The study was performed with the participation of 115 male patients diagnosed with chronic coronary heart disease. Metabolic syndrome verification was carried out using the clinical recommendations of the All-Russian Scientific Society of Cardiology (2009). Identification of the presence of anxiety-depressive states and assessment of their severity was carried out using The Hospital Anxiety and Depression scale.

Results. The study showed that among men with chronic coronary heart disease who have metabolic syndrome, the median averaged anxiety score on the Hospital Anxiety and Depression scale was significantly higher (p=0,041) compared to those without metabolic syndrome. In 17,6% of the examined patients with a combination of chronic coronary heart disease and metabolic syndrome, elevated levels of anxiety were detected. Anxiety disorders of a subclinically pronounced nature were found in 13,7% of the surveyed in this group, and clinically pronounced in 3,9%. Elevated levels of depression were detected in 17,6% of the examined patients with metabolic syndrome. At the same time, depressive disorders of both subclinically expressed and clinically expressed nature were detected with the same frequency: 7,8% vs 7,8%.

Conclusion. Among patients with chronic coronary heart disease with a comorbid course with metabolic syndrome, the number of people with clinically pronounced anxiety and depression was higher compared to those without metabolic syndrome. In men with chronic coronary heart disease in combination with metabolic syndrome with both increased levels of anxiety and increased levels of depression, 3- and 4-component clusters of metabolic syndrome, including arterial hypertension, abdominal obesity and various dyslipidemias, were more often detected.

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Author Biographies

Roman A. Yaskevich, Federal State Budgetary Scientific Institution «Scientific Research Institute of medical problems of the North»

leading researcher of the group pathology of the cardiovascular system, associate professor at department of propedeutics of internal diseases and therapy, doctor of medical science, docent

Olga L. Moskalenko, Federal State Budgetary Scientific Institution «Scientific Research Institute of medical problems of the North»

Senior Researcher, Candidate of Biological Sciences

References

Список литературы

Алексеева Н. С., Салмина-Хвостова О. И. Аффективные расстройства у пациентов с метаболическим синдромом // Acta Biomedica Scientifica. 2014.№5 (99). С. 9-12.

Ахмеджанов Н. М., Бутрова С. А., Дедов И. И. и др. Консенсус российских экспертов по проблеме метаболического синдрома в Российской Федерации: определение, диагностические критерии, первичная профилактика, лечение // Рациональная Фармакотерапия в Кардиологии. 2010. Т. 6, № 4. С. 5-12.

Барбараш О. Л., Карпов Ю. А., Кашталап В. В. и др. Стабильная ишемическая болезнь сердца. Клинические рекомендации 2020 // Российский кардиологический журнал. 2020. Т. 25, № 11. С. 4076. https://doi.org/10.15829/29/1560-4071-2020-4076

Гринштейн Ю. И., Шабалин В. В., Руф Р. Р., Шальнова С. А. Распространенность метаболического синдрома в популяции Красноярского края и особенности его ассоциации с гиперурикемией // Российский кардиологический журнал. 2020. Т. 25, № 6. С. 55-60. https://doi.org/10.15829/1560-4071-2020-3852.

Джериева И. С., Волкова Н. И., Рапопорт С. И. Ассоциация между депрессией и метаболическим синдромом // Клиническая медицина. 2015. Т. 93. № 1. С. 62-65.

Донцов А. В. Гендерные особенности тревожно-депрессивных расстройств при метаболическом синдроме // Врач. 2014. № 2. С. 72-74.

Москаленко О. Л., Смирнова О. В., Каспаров Э. В., Зайцева О. И. Диагностика метаболического синдрома на современном этапе // Siberian Journal of Life Sciences and Agriculture. 2019. Т. 11, № 5. С. 94-100. https://doi.org/10.12731/2658-6649-2019-11-5-94-100

Москаленко О. Л., Смирнова О. В., Каспаров Э. В., Каспарова И. Э. Структура психологических расстройств больных с метаболическим синдромом и неалкогольной жировой болезнью печени // Russian Journal of Education and Psychology. 2021. Т. 12, № 4-2. С. 340-348. https://doi.org/10.12731/2658-4034-2021-12-4-2-340-348

Москаленко О. Л., Смирнова О. В., Терещенко С. Ю., Каспаров Э. В. Тревожно-депрессивные расстройства у пациентов с метаболическим синдромом // Russian Journal of Education and Psychology. 2021. Т. 12, № 4. С. 118-137. https://doi.org/10.12731/2658-4034-2021-12-4-118-137

Москаленко О. Л., Яскевич Р. А. Тревожно-депрессивные расстройства у жителей Крайнего Севера и Сибири // Russian Journal of Education and Psychology. 2021. Т. 12. № 3-2. С. 113-119. https://doi.org/10.12731/2658-4034-2021-12-3-2-113-119

Москаленко О.Л., Яскевич Р.А. Тревожно-депрессивные расстройства у пациентов с артериальной гипертонией (обзор литературы) // Russian Journal of Education and Psychology. 2021. Т. 12, № 1-2. С. 185-190. https://doi.org/10.12731/2658-4034-2021-12-1-2-185-190

Песковец Р. Д., Штарик С. Ю., Евсюков А. А. Коморбидность аффективных расстройств и метаболического синдрома среди взрослого населения города Красноярска // Сибирский медицинский журнал (г. Томск). 2016. Т. 31, № 4. С. 65-68.

Ротарь О. П., Либис Р. А., Исаева Е. Н. и др. Распространенность метаболического синдрома в разных городах РФ // Российский кардиологический журнал. 2012. Т. 17, № 2. С. 55-62.

Чазова И. Е., Мычка В. Б., Литвин А. Ю. и др. Диагностика и лечение метаболического синдрома. Российские рекомендации (второй пересмотр) // Кардиоваскулярная терапия и профилактика. – 2009. – Т. 8, № 6 (S2). – С. 1-29.

Яскевич Р. А., Каспаров Э. В., Гоголашвили Н. Г. Влияние северного стажа на частоту метаболического синдрома и его компонентов у мигрантов Крайнего Севера после переезда в новые климатогеографические условия проживания // Якутский медицинский журнал. 2021. № 3 (75). С. 80-84. https://doi.org/10.25789/YMJ.2021.75.21

Яскевич Р. А., Кочергина К. Н., Каспаров Э. В. Влияние выраженности тревожно-депрессивных расстройств на качество жизни больных артериальной гипертонией // Siberian Journal of Life Sciences and Agriculture. 2019. Т. 11, № 5-2. С. 146-151. https://doi.org/10.12731/2658-6649-2019-11-5-2-146-151

Яскевич Р. А., Москаленок О.Л. Аффективные расстройства у мужчин, имеющих артериальную гипертонию в сочетании с метаболическим синдромом // Siberian Journal of Life Sciences and Agriculture. 2022. Т. 14, № 4. С. 126-145. https://doi.org/10.12731/2658-6649-2022-14-4-126-145

Baxter A., Scott K., Vos T., Whiteford H. Global prevalence of anxiety disorders: A systematic review and meta-regression // Psychological Medicine. 2013. Vol. 43, № 5. P. 897-910. https://doi.org/10.1017/S003329171200147X

Boschloo L., Reeuwijk K. G., Schoevers R. A., W. J. H. Penninx B. The impact of lifestyle factors on the 2-year course of depressive and/or anxiety disorders // J. Affect. Disord. 2014. Vol. 159. P. 73-79. https://doi.org/10.1016/j.jad.2014.01.019

Depression and Other Common Mental Disorders. Global Health Estimates. Geneva : World Health Organization, 2017. 24 p.

Hiles S.A., Révész D., Lamers F. et al. Bidirectional prospective associations of metabolic syndrome components with depression, anxiety, and antidepressant use // Depress. Anxiety. 2016. Vol. 33. P. 754-764. https://doi.org/10.1002/da.22512

Kim B., Park E. Y. The combined effect of socioeconomic status and metabolic syndrome on depression: the Korean National Health and Nutrition Examination Survey (KNHANES) // BMC Public Health. 2020. Vol. 4, № 20(1). P. 617. https://doi.org/10.1186/s12889-020-08778-3

Limon V. M., Lee M., Gonzalez B. et al. The impact of metabolic syndrome on mental health-related quality of life and depressive symptoms // Qual. Life. Res. 2020. Vol. 29, № 8. P. 2063-2072. https://doi.org/10.1007/s11136-020-02479-5

Lopresti A. L., Hood S. D., Drummond P. D. A review of lifestyle factors that contribute to important pathways associated with major depression: diet, sleep and exercise // J. Affect. Disord. 2013. Vol. 148. P. 12-27. https://doi.org/10.1016/j.jad.2013.01.014

Mattei G., Padula M. S., Rioli G. et al. Metabolic Syndrome, Anxiety and Depression in a Sample of Italian Primary Care Patients // J. Nerv. Ment. Dis. 2018. Vol. 206, № 5. P. 316-324. https://doi.org/10.1097/NMD.0000000000000807

O’Neill S., O’Driscoll L. Metabolic syndrome: a closer look at the growing epidemic and its associated pathologies // Obes. Rev. 2015. Vol. 16. P. 1-12. https://doi.org/10.1111/obr.12229

Ortiz M. S., Sapunar J. Estrés psicológico y síndrome metabólico [Longitudinal association between chronic psychological stress and metabolic syndrome] // Rev. Med. Chil. 2018. Vol. 146, № 11. P. 1278-1285. https://doi.org/10.4067/S0034-98872018001101278

Pan A., Keum N., Okereke O. I. et al. Bidirectional Association Between Depression and Metabolic Syndrome: A systematic review and meta-analysis of epidemiological studies // Diabetes Care. – 2012. – Vol. 35, № 5. – P. 1171–1180. doi: 10.2337/dc11-2055.

Pimenta A. M., Lahortiga-Ramos F., Sayon-Orea C. et al. Depression and metabolic syndrome in participants of the “Seguimiento Universidad de Navarra” (SUN) cohort study // J Affect Disord. 2021. Vol. 1, № 284. P. 183-189. https://doi.org/10.1016/j.jad.2021.02.002

Rhee S.J., Kim E.Y., Kim S.H. et al. Subjective depressive symptoms and metabolic syndrome among the general population // Prog. Neuropsychopharmacol. Biol. Psychiatry. 2014. Vol. 3, № 54. P. 223-230. https://doi.org/10.1016/j.pnpbp.2014.06.006

Saklayen M. G. The Global Epidemic of the Metabolic Syndrome // Curr Hypertens Rep. 2018. Vol. 20, № 2. P. 12. https://doi.org/10.1007/s11906-018-0812-z

Tang F., Wang G., Lian Y. Association between anxiety and metabolic syndrome: A systematic review and meta-analysis of epidemiological studies // Psychoneuroendocrinology. 2017. Vol. 77. P. 112-121. https://doi.org/10.1016/j.psyneuen.2016.11.025

Wiltink J., Michal M., Jünger C. et al. Associations between degree and sub-dimensions of depression and metabolic syndrome (MetS) in the community: results from the Gutenberg Health Study (GHS) // BMC Psychiatry. 2018. Vol. 18, № 1. P. 114. https://doi.org/10.1186/s12888-018-1691-1

World health statistics 2018: monitoring health for the SDGs, Sustainable Development Goals. Geneva: WHO, 2018. 86 p.

Zigmond A. S. The Hospital Anxiety and Depression scale // Acta Psychiatr. Scand. 1983. P. 361-370. https://doi.org/10.1111/j.1600-0447.1983.tb09716.x

References

Alekseeva N.S., Salmina-Khvostova O.I. Affektivnye rasstroystva u patsientov s metabolicheskim sindromom [Affective disorders in patients with metabolic syndrome]. Acta Biomedica Scientifica [Acta Biomedica Scientifica]. 2014. №5 (99). P. 9-12.

Akhmedzhanov N.M., Butrova S.A., Dedov I.I. et al. Konsensus rossiyskikh ekspertov po probleme metabolicheskogo sindroma v Rossiyskoy Federatsii: opredelenie, diagnosticheskie kriterii, pervichnaya profilaktika, lechenie [Consensus of Russian experts on the problem of metabolic syndrome in the Russian Federation: definition, diagnostic criteria, primary prevention, treatment]. Ratsional’naya Farmakoterapiya v Kardiologii [Rational Pharmacotherapy in Cardiology]. 2010. Vol. 6. № 4. P. 5-12.

Barbarash O. L., Karpov Yu. A., Kashtalap V. V. et al. Stabil’naya ishemicheskaya bolezn’ serdtsa. Klinicheskie rekomendatsii 2020 [Stable coronary heart disease. Clinical guidelines 2020]. Rossiyskiy kardiologicheskiy zhurnal [Russian Journal of Cardiology]. 2020. Vol. 25. № 11. P. 4076. https://doi.org/10.15829/29/1560-4071-2020-4076

Grinshteyn Yu.I., Shabalin V.V., Ruf R.R., Shal’nova S. A. Rasprostranennost’ metabolicheskogo sindroma v populyatsii Krasnoyarskogo kraya i osobennosti ego assotsiatsii s giperurikemiey [The prevalence of metabolic syndrome in the population of the Krasnoyarsk Territory and the features of its association with hyperuricemia]. Rossiyskiy kardiologicheskiy zhurnal [Russian Journal of Cardiology]. 2020. Vol. 25. № 6. P. 55-60. https://doi.org/10.15829/1560-4071-2020-3852

Dzherieva I.S., Volkova N. I., Rapoport S.I. Assotsiatsiya mezhdu depressiey i metabolicheskim sindromom [Association between depression and metabolic syndrome]. Klinicheskaya meditsina [Clinical Medicine]. 2015. Vol. 93. № 1. P. 62-65.

Dontsov A.V. Gendernye osobennosti trevozhno-depressivnykh rasstroystv pri metabolicheskom sindrome [Gender characteristics of anxiety and depressive disorders in metabolic syndrome]. Vrach [Vrach]. 2014. № 2. P. 72-74.

Moskalenko O.L., Smirnova O.V., Kasparov E.V., Zaytseva O.I. Diagnostika metabolicheskogo sindroma na sovremennom etape [Diagnostics of the metabolic syndrome at the present stage]. Siberian Journal of Life Sciences and Agriculture. 2019. Vol. 11. № 5. P. 94-100. https://doi.org/10.12731/2658-6649-2019-11-5-94-100

Moskalenko O. L., Smirnova O. V., Kasparov E. V., Kasparova I. E. Struktura psikhologicheskikh rasstroystv bol’nykh s metabolicheskim sindromom i nealkogol’noy zhirovoy bolezn’yu pecheni [The structure of psychological disorders in patients with metabolic syndrome and non-alcoholic fatty liver disease]. Russian Journal of Education and Psychology. 2021. Vol. 12. № 4-2. P. 340-348. https://doi.org/10.12731/2658-4034-2021-12-4-2-340-348

Moskalenko O.L., Smirnova O.V., Tereshchenko S.Yu., Kasparov E.V. Trevozhno-depressivnye rasstroystva u patsientov s metabolicheskim sindromom [Anxiety and depressive disorders in patients with metabolic syndrome]. Russian Journal of Education and Psychology. 2021. Vol. 12. № 4. P. 118-137. https://doi.org/10.12731/2658-4034-2021-12-4-118-137

Moskalenko O.L., Yaskevich R.A. Trevozhno-depressivnye rasstroystva u zhiteley Kraynego Severa i Sibiri [Anxiety and depressive disorders in residents of the Far North and Siberia]. Russian Journal of Education and Psychology. 2021. Vol. 12. № 3-2. P. 113-119. https://doi.org/10.12731/2658-4034-2021-12-3-2-113-119

Moskalenko O.L., Yaskevich R.A. Trevozhno-depressivnye rasstroystva u patsientov s arterial’noy gipertoniey (obzor literatury) [Anxiety and depressive disorders in patients with arterial hypertension (literature review)]. Russian Journal of Education and Psychology. 2021. Vol. 12. № 1-2. P. 185-190. https://doi.org/10.12731/2658-4034-2021-12-1-2-185-190

Peskovets R. D., Shtarik S. Yu., Evsyukov A. A. Komorbidnost’ affektivnykh rasstroystv i metabolicheskogo sindroma sredi vzroslogo naseleniya goroda Krasnoyarska [Comorbidity of affective disorders and metabolic syndrome among the adult population of the city of Krasnoyarsk]. Sibirskiy meditsinskiy zhurnal (g. Tomsk) [Siberian Medical Journal (Tomsk)]. 2016. Vol. 31. № 4. P. 65-68.

Rotar’ O.P., Libis R.A., Isaeva E. N. et al. Rasprostranennost’ metabolicheskogo sindroma v raznykh gorodakh RF [The prevalence of metabolic syndrome in different cities of the Russian Federation]. Rossiyskiy kardiologicheskiy zhurnal [Russian Journal of Cardiology]. 2012. Vol. 17. № 2. P. 55-62.

Chazova I.E., Mychka V.B., Litvin A.Yu. et al. Diagnostika i lechenie metabolicheskogo sindroma. Rossiyskie rekomendatsii (vtoroy peresmotr) [Diagnosis and treatment of metabolic syndrome. Russian recommendations (second revision)]. Kardiovaskulyarnaya terapiya i profilaktika [Cardiovascular therapy and prevention]. 2009. Vol. 8. № 6 (S2). P. 1-29.

Yaskevich R.A., Kasparov E.V., Gogolashvili N.G. Vliyanie severnogo stazha na chastotu metabolicheskogo sindroma i ego komponentov u migrantov Kraynego Severa posle pereezda v novye klimatogeograficheskie usloviya prozhivaniya [Influence of northern experience on the frequency of metabolic syndrome and its components in migrants of the Far North after moving to new climatic and geographical conditions of residence]. Yakutskiy meditsinskiy zhurnal [Yakut medical journal]. 2021. № 3(75). P. 80-84. https://doi.org/10.25789/YMJ.2021.75.21

Yaskevich R.A., Kochergina K.N., Kasparov E.V. Vliyanie vyrazhennosti trevozhno-depressivnykh rasstroystv na kachestvo zhizni bol’nykh arterial’noy gipertoniey [Influence of the severity of anxiety and depressive disorders on the quality of life of patients with arterial hypertension]. Siberian Journal of Life Sciences and Agriculture. 2019. Vol. 11. №5-2. P. 146-151. https://doi.org/10.12731/2658-6649-2019-11-5-2-146-151

Yaskevich R. A., Moskalenko O. L. Affektivnye rasstroystva u zhenshchin, imeyushchikh arterial’nuyu gipertoniyu v sochetanii s metabolicheskim sindromom [Affective disorders in women with arterial hypertension in combination with metabolic syndrome]. Siberian Journal of Life Sciences and Agriculture. 2022. Vol. 14, № 4. P. 126-145. https://doi.org/10.12731/2658-6649-2022-14-4-126-145

Baxter A., Scott K., Vos T., Whiteford H. Global prevalence of anxiety disorders: A systematic review and meta-regression. Psychological Medicine. 2013. Vol. 43. № 5. P. 897-910. https://doi.org/10.1017/S003329171200147X

Boschloo L., Reeuwijk K. G., Schoevers R. A., W. J. H. Penninx B. The impact of lifestyle factors on the 2-year course of depressive and/or anxiety disorders. J. Affect. Disord. 2014. Vol. 159. P. 73-79. https://doi.org/10.1016/j.jad.2014.01.019

Depression and Other Common Mental Disorders. Global Health Estimates. Geneva : World Health Organization, 2017. 24 p.

Hiles S.A., Révész D., Lamers F. et al. Bidirectional prospective associations of metabolic syndrome components with depression, anxiety, and antidepressant use. Depress. Anxiety. 2016. Vol. 33. P. 754-764. https://doi.org/10.1002/da.22512

Kim B., Park E. Y. The combined effect of socioeconomic status and metabolic syndrome on depression: the Korean National Health and Nutrition Examination Survey (KNHANES). BMC Public Health. 2020. Vol. 4. №20(1). P. 617. https://doi.org/10.1186/s12889-020-08778-3

Limon V. M., Lee M., Gonzalez B. et al. The impact of metabolic syndrome on mental health-related quality of life and depressive symptoms. Qual. Life. Res. 2020. Vol. 29. № 8. P. 2063-2072. https://doi.org/10.1007/s11136-020-02479-5

Lopresti A. L., Hood S. D., Drummond P. D. A review of lifestyle factors that contribute to important pathways associated with major depression: diet, sleep and exercise. J. Affect. Disord. 2013. Vol. 148. P. 12-27. https://doi.org/10.1016/j.jad.2013.01.014

Mattei G., Padula M. S., Rioli G. et al. Metabolic Syndrome, Anxiety and Depression in a Sample of Italian Primary Care Patients. J. Nerv. Ment. Dis. 2018. Vol. 206. № 5. P. 316-324. https://doi.org/10.1097/NMD.0000000000000807

O’Neill S., O’Driscoll L. Metabolic syndrome: a closer look at the growing epidemic and its associated pathologies. Obes. Rev. 2015. Vol. 16. P. 1-12. https://doi.org/10.1111/obr.12229

Ortiz M. S., Sapunar J. Estrés psicológico y síndrome metabólico [Longitudinal association between chronic psychological stress and metabolic syndrome]. Rev. Med. Chil. 2018. Vol. 146. № 11. P. 1278-1285. https://doi.org/ 10.4067/S0034-98872018001101278

Pan A., Keum N., Okereke O. I. et al. Bidirectional Association Between Depression and Metabolic Syndrome: A systematic review and meta-analysis of epidemiological studies. Diabetes Care. 2012. Vol. 35. № 5. P. 1171-1180. https://doi.org/10.2337/dc11-2055

Pimenta A. M., Lahortiga-Ramos F., Sayon-Orea C. et al. Depression and metabolic syndrome in participants of the “Seguimiento Universidad de Navarra” (SUN) cohort study. J. Affect Disord. 2021. Vol. 1. № 284. P. 183-189. https://doi.org/10.1016/j.jad.2021.02.002

Rhee S.J., Kim E.Y., Kim S.H. et al. Subjective depressive symptoms and metabolic syndrome among the general population. Prog. Neuropsychopharmacol. Biol. Psychiatry. 2014. Vol. 3. № 54. P. 223-230. https://doi.org/10.1016/j.pnpbp.2014.06.006

Saklayen M. G. The Global Epidemic of the Metabolic Syndrome. Curr Hypertens Rep. 2018. Vol. 20. № 2. P. 12. https://doi.org/10.1007/s11906-018-0812-z

Tang F., Wang G., Lian Y. Association between anxiety and metabolic syndrome: A systematic review and meta-analysis of epidemiological studies. Psychoneuroendocrinology. 2017. Vol. 77. P. 112-121. https://doi.org/10.1016/j.psyneuen.2016.11.025

Wiltink J., Michal M., Jünger C. et al. Associations between degree and sub-dimensions of depression and metabolic syndrome (MetS) in the community: results from the Gutenberg Health Study (GHS). BMC Psychiatry. 2018. Vol. 18. № 1. P. 114. https://doi.org/10.1186/s12888-018-1691-1

World health statistics 2018: monitoring health for the SDGs, Sustainable Development Goals. Geneva: WHO, 2018. 86 p.

Zigmond A. S. The Hospital Anxiety and Depression scale. Acta Psychiatr. Scand. 1983. 361-370. https://doi.org/10.1111/j.1600-0447.1983.tb09716.x


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Published
2023-02-28
How to Cite
Yaskevich, R., & Moskalenko, O. (2023). AFFECTIVE DISORDERS IN MEN WITH ARTERIAL HYPERTENSION IN COMBINATION WITH METABOLIC SYNDROME. Siberian Journal of Life Sciences and Agriculture, 15(1), 327-345. https://doi.org/10.12731/2658-6649-2023-15-1-327-345
Section
Internal Medicine

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